The Department of Dermatology at the National Taiwan University Hospital has been a division of the College of Medicine. Our mission is to provide teaching that will ensure a high degree of competence in clinical dermatology as well as special training in the basic sciences pertinent to the teaching, research, and practice of dermatology. At present, our full-time teaching faculty has 7 members and our part-time teaching faculty has 11 members.
The practice of dermatology can be traced back one century to the Skin and Venereal Disease Clinic, established in 1903. The clinic was initially a genitourinary service within the Department of Surgery in the Taihuko (Taipei) Imperial University, which was reorganized into the National Taiwan University in 1945. In 1938, separated from the Department of Surgery, the Skin and Venereal Disease Clinic was transformed into the Department of Dermatology and Urology. The Department of Dermatology was subsequently separated from the Department of Urology in 1961 and became a full-fledged department.
1.Prof. Yu’s studies showed that phototherapy-induced repigmentation of vitiligo can be explained by photo-induced production of melanocyte growth factor by keratinocytes and photo-induced migration of melanocytes (J Invest Dermatol 2003 & Exp Dermatol 2004).
2.Prof. Jee reported that IL-6 promotes tumorigenicity and anti-apoptotic activity of human BCC cell line (Oncogene 2001). She also elucidated the mechanism of IL-6-induced anti-apoptosis in BCC cells (J Invest Dermatol 2002). Furthermore, she demonstrated the pathways involved in IL-6-induced bFGF-dependent angiogenesis in BCC cell line (J Invest Dermatol 2004).
3.Prof. Jee still kept proposing project recently: Growth of melanocytes on chitoson-coated surface. In collaboration with Tai-Horng Young, Institute of Biomedical Engineering, College of Medicine and College of Engineering, national Taiwan University, Taipei, Taiwan. Since 2004 until now.
4.Dr. Chiu proposed a phase I/II study to evaluate the safety, tolerability and efficacy of autologous melanocyte transplantation in subjects with vitiligo. In collaboration with Industrial Technology Research Institute.
5.Dr. Tsai first reported the effects of glycolic acid on light-induced skin pigmentation in Asian and Caucasian subjects (J Am Acad Dermatol 2000).
6.Dr. Wang first demonstrated that epicutaneous exposure of protein antigen can induce a predominant Th2-like response with high IgE production in mice (J Immunol 1996).
7.Dr. Wang especially concentrated on the field of immunological dermatology. Several projects were proceeding at present. One of them is to clarify CD8 T cell response in murine model of atopic dermatitis and its role in pathogenesis.
Our faculty is committed to the highest level of basic and clinical research as well as training in dermatologic science. Our teaching in cutaneous biology includes the areas of physiology, immunodermatology, cell biology, molecular biology, and pathology. Our clinical teaching activities encompass a wide range of subjects, with special focus on diagnostic dermatology, aesthetic dermatology and dermatological surgery. Since making a morphological diagnosis is the heart of dermatology, we stress the importance of being visually literate. In order to teach the art and science of seeing, our faculty has an enormous collection of images of skin diseases, so that students, residents, and physicians can learn about basic morphological changes in the skin, and then integrate their observations with the associated scientific facts to have a thorough understanding of the materials.